CASR
CASR encodes the calcium-sensing receptor, a class C G-protein-coupled receptor expressed on parathyroid chief cells and renal tubule cells that detects extracellular ionized calcium and, in response, regulates parathyroid hormone secretion and renal calcium reabsorption. Common CASR variants shift the physiological calcium set-point and are associated with modest, within-normal-range differences in serum calcium, matching this dataset's calcium-status trait.
Traits CASR shapes
Markers (rsIDs)
Reference databases
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