← Glossary
Gene

GSTM1

GSTM1 encodes glutathione S-transferase mu 1, a phase II detoxification enzyme expressed mainly in the liver that conjugates glutathione to reactive electrophiles, carcinogens, and oxidative-stress byproducts to enable their elimination. The gene carries a very common copy-number deletion (null) polymorphism that abolishes enzyme activity entirely, which is the basis for the "detox enzyme" context tracked here and requires whole-genome copy-number/structural-variant reading rather than a single SNP call.

Traits GSTM1 shapes

Reference databases

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This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.