MCM6
MCM6 (minichromosome maintenance complex component 6) encodes a subunit of the MCM2-7 helicase complex that licenses and unwinds DNA during replication in dividing cells. The lactase-persistence variant rs4988235 sits within intron 13 of MCM6, in a regulatory enhancer element that controls expression of the neighboring LCT (lactase) gene in the small intestine, so this MCM6 intronic site — not the MCM6 protein itself — determines whether lactase production continues into adulthood for digesting dairy.
Traits MCM6 shapes
Markers (rsIDs)
Reference databases
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