Gene

MTHFR

MTHFR makes an enzyme that helps convert folate into a form used to process homocysteine. The common rs1801133 coding T version, which is genomic-forward A, makes a heat-sensitive enzyme with lower average activity. Its effect on blood folate and homocysteine varies with folate exposure. This common marker does not diagnose folate deficiency, inherited clotting risk, or recurrent pregnancy loss.

Traits MTHFR shapes

Folate processing (MTHFR)

Markers (rsIDs)

rs1801133

Reference databases

HGNC gene symbol report: MTHFR
NCBI Gene: MTHFR

How Biome reads this

Biome's whole-genome test reads this from one saliva sample, alongside all 3.2 billion letters of your DNA.

Biome DNA test →

This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.