← Glossary
Gene

TRPM6

TRPM6 encodes a channel-kinase fusion protein, a cation channel permeable to magnesium and calcium that is expressed predominantly in the distal convoluted tubule of the kidney and in intestinal epithelium, where it mediates active transcellular magnesium (re)absorption. Common TRPM6 variants such as rs11144134 shift blood magnesium levels within the normal range, though dietary intake and kidney function remain the dominant determinants of magnesium status.

Traits TRPM6 shapes

Markers (rsIDs)

Reference databases

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