rs671
rs671 is the ALDH2 Glu504Lys missense variant, which produces a near-inactive form of mitochondrial aldehyde dehydrogenase 2, the enzyme that clears the toxic alcohol metabolite acetaldehyde. Carriers of the Lys (A) allele break down acetaldehyde far more slowly, so it accumulates after drinking and triggers facial flushing, rapid heart rate, and nausea. This is the basis of the Alcohol flush response trait, which reflects how quickly acetaldehyde is cleared.
Traits rs671 reads
Gene
Reference databases
How Biome reads this
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