← Glossary
TraitHigh when call is present

Chemotherapy (fluoropyrimidine) tolerance (DPYD)

Chemotherapy (fluoropyrimidine) tolerance (DPYD) is a genetic trait Biome reports in its medication response panel: How well the DPD enzyme breaks down fluoropyrimidine chemotherapy drugs (5-FU, capecitabine) — lower activity raises the risk of severe side effects.

Category
Medication response
Markers
DPYD phenotype
Strength of evidence
High when call is present
DNA-test coverage
Stronger with whole genome

Genes

How Biome reads this

Biome's at-home DNA test reads this directly from one saliva sample, alongside 650,000+ other markers.

Biome DNA test

This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.