Gene

ABCG2

ABCG2 makes a transporter in the intestine, liver, and kidneys. The Q141K variant rs2231142 lowers transporter function and raises rosuvastatin exposure; CPIC uses this single SNP for rosuvastatin guidance. The same variant is linked to higher blood uric acid and higher overall gout odds, but it does not measure a person's uric-acid clearance or diagnose gout.

Traits ABCG2 shapes

Statin & urate-drug transport (ABCG2)
Uric-acid clearance & gout risk (ABCG2)

Markers (rsIDs)

rs2231142

Reference databases

HGNC gene symbol report: ABCG2
NCBI Gene: ABCG2

How Biome reads this

Biome's whole-genome test reads this from one saliva sample, alongside all 3.2 billion letters of your DNA.

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This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.