BCHE
BCHE encodes butyrylcholinesterase (pseudocholinesterase), a liver-derived enzyme circulating in blood that hydrolyzes choline-ester drugs, including the anesthesia muscle relaxants succinylcholine and mivacurium. Reduced-activity variants such as rs1799807 (the "atypical" allele) and rs1803274 slow this breakdown, so carriers can experience markedly prolonged neuromuscular blockade and delayed return of spontaneous breathing after these drugs are given during anesthesia.
Traits BCHE shapes
Markers (rsIDs)
Reference databases
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