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TraitResearch-grade — no prescribing guideline

GLP1R response to GLP-1 weight-loss medicines

GLP1R response to GLP-1 weight-loss medicines is a genetic trait Biome reports in its medication response panel: In one large study, each T copy was linked to about 1.7 pounds more weight loss and more nausea or vomiting on semaglutide or tirzepatide. The weight result repeated in another study; the side-effect result has not.

Category
Medication response
Markers
GLP1R rs10305420
Strength of evidence
Research-grade — no prescribing guideline
DNA-test coverage
If covered

Genes

Markers (rsIDs)

How Biome reads this

Biome's whole-genome test reads this from one saliva sample, alongside all 3.2 billion letters of your DNA.

Biome DNA test

This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.