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TraitHigh for CPIC high-risk medicines when G6PD deficiency is confirmed

Medication-triggered red blood cell breakdown (G6PD)

Medication-triggered red blood cell breakdown (G6PD) is a genetic trait Biome reports in its medication response panel: G6PD deficiency can make certain medicines break down red blood cells. CPIC recommends avoiding high-risk medicines when deficiency is confirmed. For people with one normal and one deficient copy, a blood enzyme test is needed because DNA alone cannot predict enzyme activity.

Category
Medication response
Markers
G6PD genotype plus enzyme activity when genotype is variable or indeterminate
Strength of evidence
High for CPIC high-risk medicines when G6PD deficiency is confirmed
DNA-test coverage
Stronger with whole genome

Genes

How Biome reads this

Biome's whole-genome test reads this from one saliva sample, alongside all 3.2 billion letters of your DNA.

Biome DNA test

This page is for educational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Genetic results describe tendencies and predispositions, not diagnoses. Always consult a licensed clinician before making decisions about your health, medications, or supplements.