rs10246939
rs10246939 is the TAS2R38 c.886A>G variant producing the Ile296Val substitution, one of three coding changes (with rs713598 Ala49Pro and rs1726866 Val262Ala) that define the gene's two common haplotypes, PAV and AVI. The PAV haplotype forms a bitter-taste receptor with high sensitivity to compounds like PTC and PROP, while AVI/AVI carriers are relative non-tasters, so diplotype at these three sites largely determines bitter-taste sensitivity.
Traits rs10246939 reads
Gene
Reference databases
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